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Fig 1.

Exemplary segmentation of a coronal T1w Dixon-VIBE-dataset (A). Corresponding fat only images (B). A whole kidney mask is generated using thresholding and active contours (C). Next the renal sinus fat is segmented using thresholding of fat isointense voxels (D).

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Fig 1 Expand

Fig 2.

Inclusion flow chart.

N = 366 study subjects were finally included for analysis.

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Table 1.

Demographics, cardiovascular risk factors and MRI parameters of the study participants.

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Fig 3.

Boxplots with density curves displaying the distribution of renal and sinus fat volumes according to glycemic status.

There was a considerable increase between controls and subjects with prediabetes particularly for renal sinus fat.

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Table 2.

Regression model with adjustments for age, gender and glycemic status.

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Table 2 Expand

Table 3.

Regression model with adjustments for age, VAT, HDL, LDL, urine albumin/creatinine, liver fat, GFR, gender, hypertension yes/no and glycemic status.

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Table 4.

Regression model with adjustments for age, gender and VAT.

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Fig 4.

Scatter diagrams showing the correlation of the VAT with the glycemic groups.

There was a significant correlation between VAT and renal sinus fat particularly for healthy controls and individuals with diabetes.

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Table 5.

Pearson’s correlation coefficients of VAT and renal volumes with corresponding 95% CI stratified by glycemic status.

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