Fig 1.
Flow diagram of study identification and selection.
Table 1.
Bias assessment with Quips tool [38].
Table 2.
Study and patient related characteristics of included studies.
Fig 2.
Unadjusted odds ratios for elevation in preoperative cTn to predict short-term adverse outcome.
Forest plot showing the individual and pooled unadjusted odds ratios from the included studies. cTn = Cardiac troponin. CI = Confidence interval. # = Number of.
Table 3.
Association between cardiac troponin and adverse outcome.
Fig 3.
Adjusted odds ratios for elevation in preoperative cTn to predict short-term adverse outcome.
Forest plot showing the individual and pooled adjusted odds ratios from the included studies. cTn = Cardiac troponin. CI = Confidence interval. # = Number of.
Fig 4.
Unadjusted odds ratios for elevation in preoperative cTn to predict long-term adverse outcome.
Forest plot showing the individual and pooled unadjusted odds ratios from the included studies. cTn = Cardiac troponin. CI = Confidence interval. # = Number of.
Fig 5.
Adjusted hazard ratios for elevation in preoperative cTn to predict long-term adverse outcome.
Forest plot showing the individual and pooled adjusted hazard ratios from the included studies. cTn = Cardiac troponin. CI = Confidence interval. # = Number of.
Fig 6.
Unadjusted odds ratios for an absolute perioperative change in cTn to predict short-term adverse outcome.
Forest plot showing the individual and pooled unadjusted odds ratios from the included studies. cTn = Cardiac troponin. CI = Confidence interval. # = Number of.
Fig 7.
Summary receiver operating characteristic (SROC) curve for prognostic performance of preoperative cTn to predict short-term adverse outcome.
Filled dots = observed data. Unfilled dot = pooled sensitivity (0.43 [CI 0.29–0.58]) and specificity (0.85 [CI 0.73–0.94]). Black curve = SROC curve (AUC = 0.68). Black-lined region = 95% confidence region. Dashed-lined region = 95% prediction region.