Fig 1.
16S rRNA based phylogeny analysis of 32 Mycobacteria strains belonging to different species: Differentiation into rapid and lowly growing Mycobacteria.
The 16S rRNA gene-based phylogenetic tree clearly distinguishes Mycobacterium grouping based on the growth rates. UM_RHS and UM_ NYF were clustered in the rapid growing mycobacterial group.
Fig 2.
Supermatrix tree of five markers (hsp65, rpoB, tuf, sodA and 16S rRNA).
UM_RHS and UM_NYF are closest to M. cosmeticum, supported by a high bootstrap value of 85%.
Fig 3.
Average nucleotide analysis for 37 Mycobacterium species.
The ANI values of UM_NYF and UM_RHS against M. cosmeticum DSM44829 are above 95%, supporting that these strains belong to the species M. cosmeticum.
Fig 4.
RAST functional categories of UM_RHS and UM_NYF genes.
Number of genes in UM_RHS in comparison to UM_NYF which belong to specific RAST functional categories with M. cosmeticum DSM 44829 as the reference genome.
Table 1.
RNAs identified by RAST in the genomes of UM_NYF and UM_RHS.
Table 2.
RAST predicted genes related to gene transfer in the genomes of UM_NYF and UM_RHS.
Fig 5.
Genomic structure of M. cosmeticum genomes.
The genome structures are generally conserved among three studied genomes (UM_RHS, UM_NYF and DSM44829).
Fig 6.
The M. cosmeticum DSM 44829, UM_RHS and UM_NYF have generally shared a high number of common gene families.
Fig 7.
Predicted virulence genes in the genomes of M. cosmeticum DSM44829, UM_RHS and UM_NYF.