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Fig 1.

a) Serum tau protein levels within 6 hours from injury (diffuse axonal injury group vs. non-diffuse axonal injury group). Serum tau protein levels of diffuse axonal injury group were significantly higher than non-diffuse axonal injury group (P = 0.02). P values were calculated using Mann-Whitney’s U-test. Error bars indicate inter-quartile range. *P<0.05. b) Receiver Operating Characteristic Curve for serum tau protein within 6 hours from injury for diffuse axonal injury diagnosis. The area under the curve (AUC) was 0.690 (95% CI 0.512–0.867) with 74.1% sensitivity and 69.2% specificity at a serum tau protein level of 1.5 pg/mL.

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Fig 1 Expand

Table 1.

Baseline characteristics of study patients with DAI and non- DAI.

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Table 1 Expand

Fig 2.

Serum tau protein levels within 6 hours from injury (favorable outcome group vs. unfavorable outcome group).

Serum tau protein levels of unfavorable outcome group were not significantly higher than favorable outcome group (P = 0.19). P values were calculated using Mann-Whitney’s U-test. Error bars indicate inter-quartile range.

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Fig 2 Expand

Table 2.

Baseline characteristics of study patients by the neurological outcome at hospital discharge.

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Table 2 Expand