Fig 1.
Decision-tree for patients with sepsis.
ABX = Antibiotics.
Fig 2.
Decision-tree for patients with LRTI.
ABX = Antibiotics.
Table 1.
Effectiveness input data.
Table 2.
Resource use.
Table 3.
Cost input data for sepsis and LRTI, all based on the US.
Fig 3.
Flow chart of systematic literature review.
Table 4.
Results for patients with sepsis and LRTI.
Fig 4.
Tornado diagram showing the results of the sensitivity analysis for sepsis on the total costs per patient in comparison to the base case values of the main analysis.
The tornado diagram shows to what degree changes in an input variable influence the total costs of PCT-guided care. While all other parameters are being held equal, the value of one input parameter is varied by + or– 25%. The tornado diagram shows the difference of this result to the result of the primary analysis, in which the values as defined in the input parameter tables are used.
Fig 5.
Tornado diagram showing the results of the sensitivity analysis for LRTI on the total costs per patient in comparison to the base case values of the main analysis.