Table 1.
Baseline sociodemographic and clinical characteristics of the study sample.
Table 2.
Plasma concentrations of inflammatory mediators in participants grouped according to the type of substance use disorder.
Table 3.
Plasma concentrations of inflammatory mediators in the cocaine and alcohol groups according to comorbid depression.
Table 4.
Plasma concentrations of inflammatory mediators in the cocaine and alcohol groups according to the type of depression.
Table 5.
Binary logistic regression models for predicting cocaine-induced depression through plasma concentrations of inflammatory mediators, sex, age, and BMI.
Fig 1.
ROC analysis and scatter dots for two logistic models to distinguish primary MDD from cocaine-induced MDD in the cocaine group.
(A) ROC analysis of a full model: TNF-α, IL-1β, CXCL12, CCL2, CCL11 CX3CL1, sex, age and BMI; and a scatter plot for the predictive probabilities. (B) ROC analysis of an adjusted model: CXCL12, CCL11 and sex; and a scatter plot for the predictive probabilities. Lines on the scatter plots are means and SD.