Table 1.
Demographic and clinical characteristics of human subjects.
Fig 1.
The alpha-diversity indices between SLE patients (red) and healthy controls (blue).
Fig 2.
Gut microbial composition of SLE patients and healthy controls.
(a) PCoA score plots of SLE patients (red) and healthy controls (blue) based on the gut microbial composition. (b) PLS-DA score plots of SLE patients(red) and healthy controls (blue) based on the gut microbial composition. (c) Species correlation network analysis on genus level. (The green line represents positive correlation, the red line represents negative correlation, the node represents species and the node size represents species abundance.)
Fig 3.
Differences in gut microbial between SLE patients and healthy controls.
(a) Significantly altered gut microbiota between SLE patients (red) and healthy controls (blue) at the phylum, family and genus levels. (b) Receiver operating characteristic (ROC) curves demonstrating the performance of significantly altered microbial genera in SLE patients.
Fig 4.
Analysis of intestinal microbial function of SLE patients.
(a) Significantly alerted abundance of samples between SLE patients(red) and healthy control (blue) based on GOC data. (b) Significantly alerted pathway abundance of samples between SLE patients(red) and healthy control (blue) based on KEGG data.