Table 1.
General information of all patients, CT-characteristics as well as ultrasound-findings in patients with liver metastasis.
Table 2.
Three main categories describing the characteristics of metastatic liver lesions of neuroendocrine tumors in 3-phasic CT-imaging.
Fig 1.
A metastatic lesion in segment 3 of the liver of a single patient in long term follow-up (CT-scan and ultrasound) demonstrating minimal growth over eight years (A) ultrasound (B) CT-scan with zoomed-in calcified lesion.
Fig 2.
The non-contrast phase, arterial phase, portal venous phase and delayed phase in a 4-phasic MDCT following bolus administration of Intravenous contrast medium in 3 patients with MEN syndrome and pathological proven liver metastasis (arrows).
(A) Typical appearance of a hypervascular liver metastasis in segment 6 with avid early contrast enhancement that may wash out or become isodense (and difficult to detect) on more delayed post-contrast images (group i) (B) Hypodense liver metastasis in segment 8 with low-grade contrast enhancement in the arterial phase and rapid wash out in the portal venous phase (group ii) (c) Calcified metastatic lesion in segment 4a with a faint peripheral contrast-enhancement in arterial phase (group iii).
Table 3.
The prevalence of liver calcification as well as calcified metastatic lesions MEN1 and MEN2 groups.
Table 4.
Characteristics of the most common differential diagnoses of hepatic lesions in patients with MEN-syndrome.
Table 5.
The values of calcitonin as well as CEA at the time of CT-Examination in Patients with MEN2-syndrome.
Fig 3.
A patient with MEN1 and a liver metastasis.
The liver metastasis shows a blurred marginal Enhancement in arterial phase and rapid washout in late phases (group ii) with a prominent uptake in 68Ga-DOTA-somatostatin analogue-PET/CT, demonstrating highly homogeneous tumor cell density.