Table 1.
LFI tests approved for limited evaluation of performance by WHO.
Fig 1.
Flow chart of PCR analysis of samples.
altona assay = RealStar Filovirus Screen RT-PCR kit 1.0; Trombley assay = PHE Zaire-specific RT-PCR Trombley assay.
Table 2.
Comparison of altona and Trombley RT- PCR results.
Table 3.
Performance of LFIs compared to altona RT-PCR*.
Fig 2.
Sensitivity of LFIs for samples grouped according to altona Ct value (black) and Trombley Ct value (blue).
Bars represent 95% confidence intervals for sensitivity. For the altona assay there were 32, 37, 24, 14 and 19 samples in each RT-PCR Ct group from <20 to ≥29. The corresponding sample sizes for the Trombley assay were 52, 32, 16, 14 and 42.
Table 4.
Performance of LFIs on plasma samples using Trombley assay as bench mark assay*.