Table 1.
The criteria of the designed primers for high resolution melting assays.
Table 2.
The sociodemographic data for the cases and controls.
Table 3.
Prescribed medications at the time of sample collection.
Fig 1.
High-resolution melting analysis.
A representative result of the normalized melting curves for (A) each genotype G/G, A/A and G/A BDNF rs6265 (C) BDNF rs1048218 and (E) BDNF rs1048220 and temperature shifted difference plot for (B) the three genotypes G/G, A/A and G/A of BDNF rs6265 (D) BDNF rs1048218 and (F) BDNF rs1048220. (G) Representative results for the G/G, G/A, and A/A genotypes obtained from the sequencing of BDNF rs6265. A representative result for the monomorphic genotype obtained from the sequencing of (H) BDNF rs1048218 and (I) BDNF rs1048220.
Table 4.
The stratification of genotypes among male and female case and control subjects.
Table 5.
The stratification of genotypes among the ethnicities of the cases and controls.
Table 6.
The summary of the distribution of the alleles and genotypes among the cases and controls.
Table 7.
The association of BDNF rs6265 to MDD (n = 599) with crude odds ratio of the different inheritance models.
Table 8.
The association of BDNF rs6265 to MDD (n = 598) upon the adjustment of odds ratio.
Fig 2.
Measurement of plasma BDNF level.
(A) The plasma BDNF level between the overall controls and cases (B) among subjects with wild type G/G, (C) heterozygous G/A and (D) homozygous A/A genotypes. The plasma BDNF level according to the different genotypes among (E) controls or (F) cases. (G) The plasma BDNF levels among the three genotypes regardless of subject groups (cases and controls). Results are represented as mean±SEM.