Table 1.
Serum and urinary EGF concentrations in the entire population, in adults and in children.
Table 2.
Age-specific serum EGF concentrations.
Table 3.
Age-specific urinary EGF concentrations.
Fig 1.
Correlations of serum EGF with age (A; r = -0.873; p<0.001) and with urinary EGF (B; r = 0.716; p<0.001). EGF was not corrected for body surface to avoid spurious correlation. sEGF: serum epidermal growth factor; uEGF: urinary epidermal growth factor; uCr: urinary creatinine; BSA: body surface area.
Fig 2.
Correlations of urinary EGF with age (A; r = -0.855; p<0.001) and with creatinine clearance (B; r = 0.524; p<0.001). uEGF: urinary epidermal growth factor; uCr: urinary creatinine; BSA: body surface area.
Fig 3.
Serum EGF concentrations between sexes per age subcategory.
In females >13y, urinary EGF is significantly higher compared to males. * p<0.05. uEGF: urinary epidermal growth factor; uCr: urinary creatinine; BSA: body surface area.
Fig 4.
Correlation between serum EGF and serum magnesium (A; r = 0.597; p<0.001) and serum EGF and the FE Mg2+ (B; r = -0.200; p = 0.048). sEGF: serum epidermal growth factor; BSA: body surface area; sMg2+: serum magnesium; FE Mg2+: fractional excretion of magnesium.
Fig 5.
Correlation between urinary EGF and serum magnesium (A; r = 0.583; p<0.001) and urinary EGF and the FE Mg2+ (B; r = -0.248; p = 0.014). uEGF: urinary epidermal growth factor; uCr: urinary creatinine; BSA: body surface area; sMg2+: serum magnesium; FE Mg2+: fractional excretion of magnesium.
Table 4.
Summary of the univariate correlation analysis, depicting the different variables in relation to serum and urinary EGF concentrations.
Table 5.
Independent variables related to serum EGF.
Table 6.
Independent variables related to urinary EGF.