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Fig 1.

Examples of artifacts.

For each artifact OCTA enface and B-Scans are shown. Red arrows indicate the artifacts, red lines indicate the corresponding B-scan. (A) segmentation artifact retina avascular layer. (B) out of window artifact retina layer depth encoded. (C) motion artifact retina layer.

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Table 1.

Overview of artifacts including their cause and definition.

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Table 2.

Absolute frequency and central thickness of macular edema by diagnosis.

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Table 2 Expand

Fig 2.

Different types of identified artifacts and their relative frequencies per entire OCTA scan.

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Fig 3.

Frequencies of various artifacts in different segmentations of the OCTA scans.

Overall, the interpretability of the OCTA images was graded sufficient in 25% of assessments (19/75, 95% confidence interval (CI): 16%-37%) and excellent in 65% (49/75, 95% CI: 53%-76%), adding up to 91% of OCTA assessments deemed of an acceptable quality allowing for clinical interpretation (68/75, 95% CI: 82%-96%). Also, the presence of macular edema was associated with poorer interpretability: While 85.7% of OCTA images of eyes without ME were excellently interpretable, 76.9% of OCTA imaging results with a ME < 400 μm and 33.3% with a ME > 400 μm (p<0.01; Fisher`s exact test) were deemed of sufficient quality for clinical interpretability.

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