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Fig 1.

Flowchart of the inclusion and exclusion for subjects based on the dataset surveyed in Korea by the National Health Insurance System (NHIS).

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Fig 1 Expand

Table 1.

Demographics and clinical characteristics of the patients with ankylosing spondylitis and control group.

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Table 1 Expand

Fig 2.

Comparison of the cumulative incidence of dementia (overall, Alzheimer’s, and vascular) in the AS and control groups.

The Kaplan-Meier curves with cumulative hazards showed the significantly higher incidence of overall dementia (A) and Alzheimer’s dementia (B) in the AS group compared to the control group (p < 0.001). The cumulative incidence of VD was not statistically different between the two groups (C).

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Fig 2 Expand

Table 2.

Calculated hazard ratios of dementia (Alzheimer’s and vascular) in the AS and control groups.

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Table 2 Expand

Fig 3.

Subgroup analyses of risk for dementia in the AS group.

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Fig 3 Expand