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Table 1.

Major causative factors for drugs to be classified as off-label or unlicensed (n = 626 off-label, n = 18 unlicensed).

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Table 2.

Frequency and percentage of off-label and unlicensed drug use for the 20 most frequently prescribed drugs (n = 868).

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Table 2 Expand

Table 3.

Frequency of off label and unlicensed prescribing within each EMEA age classification group, as well as total number of prescriptions per age group.

P value was obtained through a Fisher’s Exact test, due to the small number of unlicensed medicines.

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Table 3 Expand

Table 4.

Frequency of prescribing with respect to category based on route of administration.

P value was obtained using a Fisher’s Exact test.

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Table 4 Expand

Table 5.

Frequency of off label and unlicensed prescribing for each ATC class, and as a percentage of overall prescribing for each ATC class (n = 1160).

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Table 5 Expand

Table 6.

Number (percentage) of patients who received at least one of the drugs in the given groups.

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Table 6 Expand

Table 7.

Frequency of licensed, off-label and unlicensed drugs prescribed to paediatric patients in the six most common WHO major diagnostic categories.

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Table 7 Expand