Fig 1.
Probability of DLT as function of dose.
Table 1.
Percentage (Number) of doses relative to each discrete dose scheme which are optimal doses based on the optimal MTD interval (True MTD ± 0.15 × True MTD).
Table 2.
Percentage (Number) of doses relative to each discrete dose scheme which are optimal doses based on the optimal toxicity interval (θ ± 0.10).
Fig 2.
Absolute bias and RMSE as a function of sample size and dose scheme.
Fig 3.
DLT average and percentage of trials such that the observed DLT probability is inside the interval [θ − 0.1; θ + 0.1]as a function of true distribution and dose scheme.
Fig 4.
Percentage of trials with the estimated MTD inside the optimal MTD interval and average percentage of patients receiving doses inside the optimal MTD interval as a function of true sample size and dose scheme.
Fig 5.
Percentage of trials with the estimated MTD inside the toxicity optimal interval and average percentage of patients receiving doses inside the optimal toxicity interval as a function of true distribution and dose scheme.