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Fig 1.

Algorithmic functionality of automated bone-VOI delineation and metastasis load quantification with EBONI in an exemplary patient with known osseous metastases of prostate cancer.

csv = comma-separated values; HC = healthy controls. This figure was originally published in JNM [10]. Hammes et al. EBONI: A Tool for Automated Quantification of Bone Metastasis Load in PSMA PET/CT. J Nucl Med. 2018 Jul;59(7):1070–1075 by the Society of Nuclear Medicine and Molecular Imaging, Inc.

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Fig 2.

Exemplary PET dataset (a) and placement of VOIs (b,c). Red-dotted area was excluded from the analysis to avoid spillover into bone voxels caused by uptake in salivary and lacrimal glands.

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Fig 3.

a) Average SUVs in unaffected bone tissue in 17 patients without bone metastases. b) SUVmean and SUVmax in a total of seven bone metastases in the group of patients with bone metastases.

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Table 1.

Quantitative results in bone negative group. Average values and standard deviation.

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Table 2.

Quantitative results in bone metastases.

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Table 2 Expand