Fig 1.
Each of the main two groups (Stressed and Non-stressed) had three subgroups: non-stressed: control vehicle, control PGB, control naïve; and stressed: Posttraumatic stress disorder (PTSD) vehicle, PTSD Pre-PGB (prophylactic), PTSD Post-PGB (non-prophylactic). Mean total body weight is reported with the standard error of the mean (SEM).
Fig 2.
ANCOVA for total water intake weight.
Each of the main two groups (Stressed and Non-stressed) had three subgroups: non-stressed: control vehicle, control PGB, control naïve; and stressed: Posttraumatic stress disorder (PTSD) vehicle, PTSD Pre-PGB (prophylactic), PTSD Post-PGB (non-prophylactic). Mean total water intake weight is reported with the SEM. Asterisks denote statistical significance at p < .05. PTSD-Post-PGB was significantly less than PTSD-Pre-PGB and all three control groups. PTSD Veh was significantly lower than Con-Veh, Con-PGB, and PTSD-Pre-PGB. PTSD-Pre-PGB was significantly higher than Con-Naïve.
Fig 3.
ANCOVA for total food intake weight.
Each of the main two groups (Stressed and Non-stressed) had three subgroups: non-stressed: control vehicle, control PGB, control naïve, and stressed: Posttraumatic stress disorder (PTSD) vehicle, PTSD Pre-PGB (prophylactic), PTSD Post-PGB (non-prophylactic). Mean total food intake weight is reported with the SEM. Asterisks denote statistical significance at p < .05. PTSD-Pre-PGB was significantly higher than the PTSD-Post-PGB.
Fig 4.
ANOVA of Mean Open-Arm Time Ratio (percent) from Elevated Plus-Maze (EPM) and Standard Error of the Mean (SEM).
Each of the main two groups (Stressed and Non-stressed) had three subgroups: non-stressed: control vehicle, control PGB, control naïve, and stressed: Posttraumatic stress disorder (PTSD) vehicle, PTSD Pre-PGB (prophylactic), PTSD Post-PGB (non-prophylactic). Asterisks denote statistical significance at p < .05. PTSD vehicle and PTSD Post-PGB post-treatment had significantly lower mean open arm time ratio when compared to control. PTSD Post-PGB had significantly lower mean open arm time ratio when compared to Control PGB.
Fig 5.
ANOVA of Time in Zone1 (Platform Zone) from Morris water maze (MWM) and Standard Error of the Mean (SEM).
Each of the main two groups (Stressed and Non-stressed) had three subgroups: non-stressed: control vehicle, control PGB, control naïve; and stressed: Posttraumatic stress disorder (PTSD) vehicle, PTSD Pre-PGB (prophylactic), PTSD Post-PGB (non-prophylactic). Mean total body weight is reported with the standard error of the mean (SEM). There was not a significant difference between the six groups.
Fig 6.
ANOVA of Mean Time Mobile from Forced Swim test (FST) and Standard Error of the Mean (SEM).
Each of the main two groups (Stressed and Non-stressed) had three subgroups: non-stressed: control vehicle, control PGB, control naïve; and stressed: Posttraumatic stress disorder (PTSD) vehicle, PTSD Pre-PGB (prophylactic), PTSD Post-PGB (non-prophylactic). There was no significant difference between the six groups.