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Fig 1.

PRISMA flow diagram of evaluated studies for randomized controlled trials for efficacy of specific probiotics for the prevention or treatment of various diseases, searched from inception of databases to June 2018.

Outcomes were extracted from randomized controlled trials (RCT) with a primary outcome and may have included additional secondary outcomes and/or additional treatment arms per trial.

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Fig 1 Expand

Table 1.

Examples of 25 probiotic products available on the commercial market.

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Table 1 Expand

Fig 2.

Clinical decision algorithm for choosing an appropriate probiotic product.

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Fig 2 Expand

Table 2.

Graded recommendations for probiotic formulations for the prevention or treatment of 19 different types of diseases.

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Table 2 Expand