Fig 1.
The Fulton Index (A; weight of the right ventricle (RV) / weight of the left ventricle (LV) + septum) and RV systolic pressure (B) in mice after pulmonary artery banding (PAB) or sham surgery (control). Data reported as mean ± SEM. Statistical differences determined by two-tailed unpaired Student’s t-test.
Table 1.
Weight trends in mice after pulmonary artery banding (PAB) or sham surgery (control).
Fig 2.
The 24-hour means ± SEM for percent time in Wake, NREM sleep, and REM sleep in mice after pulmonary artery banding (PAB) or sham surgery (control).
The y-axis on the left refers to percentage of time for Wake and NREM sleep and the y-axis on the right refers to percentage of time for REM sleep. Statistical differences determined by two-tailed unpaired Student’s t-test.
Fig 3.
Circadian patterns for Wake (A), NREM sleep (B), REM sleep (C), and Delta Density (D) in mice after pulmonary artery banding (PAB) or sham surgery (control). Data reported as the mean ± SEM on a 2 hourly basis throughout the circadian period. The light region of each graph depicts the light period and the dark region of each graph depicts the dark period. Sleep stage is reported based on a percentage of time at each time-point. Delta density was averaged in two-hour increments and reported as a fraction of the 24-hour average in each mouse. Statistical differences determined by two-way ANOVA are reported in the text.
Table 2.
Sleep architecture in mice after pulmonary artery banding (PAB) or sham surgery (control).