Fig 1.
Workflow for empiric treatment of febrile neutropenia in haematology unit.
Abbreviations: ATR-Aztreonam, AMK-Amikacin, CEF-Cefepime, GM-Galactomannan, CRP- C-reactive protein, G+-Gram positive bacteria cultured, HR–Heart rate, IMI-Imipenem, MER-Meropenem, PCT-Procalcitonin, VAN-Vancomycin, PTZ- Piperacillin-tazobactam, PCR- Polymerase Chain Reaction. *Check amikacin levels, consider stopping after 72 hours if cultures negative & patient is stable # then test GM levels weekly till Absolute Neutrophil Count >1000. ————Alternative strategies in workflow.
Table 1.
Baseline characteristics.
Table 2.
Antibiotic use in the 2 years under study.
Table 3.
New cases of MRSA & VRE in the 2 years under study.
Table 4.
Mortality in the 2 years under study.
Table 5.
Bacteraemia & antibiotic resistance in Gram-negative strains of blood isolates.