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Table 1.

Prevalence of urticaria and main gastrointestinal complaints in all 1426 consecutive patients.

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Table 2.

Prevalence of gastrointestinal complaints by the presence or absence of urticaria in all 1426 consecutive patients.

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Table 3.

Demographic and clinical features of patients suffering from gastroesophageal reflux disease (GERD) and/or urticaria according to different clinical presentations.

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Fig 1.

Blood eosinophils and total IgE levels, according to different clinical presentations of gastroesophageal reflux disease (GERD) and/or urticaria.

Eosinophils and total IgE are significantly more elevated in all cases of urticaria and GERD overlap syndrome (UGOS) compared to isolated cases of GERD or urticaria. To be noted in the figure, where some of the significant differences are highlighted, how both values show a stepwise increase from the isolated GERD group up to the chronic urticaria and GERD overlap syndrome (Chronic UGOS) group. *: p <0.00001; **: p = 0.0018; ***: p = 0.003; ****: p = 0.028; N.S. = Not significant.

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Table 4.

Total IgE and Eosinophils blood count analysed by different clinical presentations and after recoding into categories of approximately equivalent size patients suffering from gastroesophageal reflux disease (GERD) and/or urticaria.

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Table 5.

Factors independently associated with urticaria and GERD overlap syndrome (UGOS) compared to patients suffering from isolated urticaria [A] or isolated gastroesophageal reflux disease (GERD) [B].

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Table 6.

Association between chronic urticaria and GERD overlap syndrome (Chronic UGOS) with serum total IgE and eosinophils blood count in patients suffering from gastroesophageal reflux disease (GERD) [A] or chronic urticaria [B].

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Table 7.

Esophageal endoscopic findings in 205 patients suffering from gastro-esophageal reflux disease (GERD) with or without the overlap of chronic spontaneous urticaria.

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