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Fig 1.

Flowchart of included patients.

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Table 1.

Patient characteristics.

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Table 1 Expand

Fig 2.

Proportional volume change of all liver metastases for each patient along with the total number of lesions (All), partial response (PR) and complete responding (CR) number of lesions.

Note the spread of lesion volume change between and within individual patients.

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Fig 2 Expand

Fig 3.

Median lesion size for the compared groups.

CR lesions were significantly smaller at baseline than the other lesions.

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Fig 3 Expand

Fig 4.

ROC curves of the PR (a) and CR (b) model for the best and worst training (solid) and the validation set (dashed).

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Fig 4 Expand

Table 2.

Top 10 important features according to the average decrease in Gini index over the 18 training models (features with a higher decrease tend to better split mixed nodes into single class nodes) and correlation coefficients of features with lesion volume.

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Table 2 Expand