Table 1.
Neuropsychological status of HIV-IC and HAND.
Table 2.
Regions showing significant differences in rsfMRI values between the groups.
Fig 1.
(Top left) ANOVA results between HAND, HIV-IC and HC. Green clusters are voxels with significant ANOVA results. (Middle left) t-test results between HIV-IC and HC. Blue clusters represent lower ReHo regions of HIV-IC and red clusters represent the opposite. (Bottom left) t-test results between HAND and HC. Blue clusters represent lower ReHo regions of HAND and red clusters represent the opposite. (Right) t-test results between HAND and HIV-IC. Blue clusters represent lower ReHo regions of HAND and red clusters represent the opposite.
Fig 2.
(Top) ANOVA results between HAND, HIV-IC and HC. Green clusters are voxels with significant ANOVA results. (Middle) t-test results between HIV-IC and HC. Blue clusters represent lower ALFF regions of HIV-IC and red clusters represent the opposite. (Bottom) t-test results between HAND and HC. Blue clusters represent lower ALFF regions of HAND and red clusters represent the opposite. There was no significant voxel in comparison between HAND and HIV-IC.
Fig 3.
The results of fALFF analysis.
(Top left) ANOVA results between HAND, HIV-IC and HC. Green clusters are voxels with significant ANOVA results. (Bottom left) t-test results between HAND and HC. Blue clusters represent lower ALFF regions of HAND, and there was no significant voxel for the opposite. (Right) t-test results between HAND and HIV-IC. Blue clusters represent lower ALFF regions of HAND, and there was no significant voxel for the opposite. No significant voxel was found in a comparison between HIV-IC and HC.
Table 3.
Correlation analysis of selected ROIs and cognitive function tests.
Fig 4.
The results of correlation analysis between mean standardized rsfMRI values and NP test scores.
(A) The left panel shows the ROI of the primary sensorimotor area which showed significant difference in ReHo values between HAND and HIV-IC. Scatter plots depicted in the right panel show significant correlations between mean ReHo values in the ROI and NP test scores. (B) The left panel shows the ROI of the orbitofrontal cortex which showed significant difference in fALFF values between HAND and HIV-IC. Scatter plots depicted in the right panel show significant correlations between mean fALFF values in the ROI and NP test scores. (C) Scatter plots show significant correlations between NP test scores and the rsfMRI values where standardized fALFF values in the orbitofrontal cortex are subtracted from standardized ReHo values in the primary sensorimotor area.