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Fig 1.

Epidemic curve of influenza virus-positive cases.

Monthly distribution of total ILI cases and influenza A and B virus-positive cases in Mongolia from September 2013 to September 2017.

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Fig 2.

Weekly distribution of influenza B viruses between 2013 and 2017 in Mongolia.

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Fig 3.

Phylogenetic tree based on HA amino acid sequences of B/Victoria lineage viruses circulated in Mongolia from 2012 to 2017.

The phylogenetic tree was created by the neighbor-joining method (1000 bootstrap replicates). Blue is for Mongolian strains, red is for vaccine strains, and black is for reference strains.

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Fig 4.

Phylogenetic tree based on HA amino acid sequences of B/Yamagata lineage viruses circulated in Mongolia from 2012 to 2016.

The phylogenetic tree was created by the neighbor-joining method (1000 bootstrap replicates). Mongolian strains (blue), vaccine strains (red), reference strains (black).

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Table 1.

Amino acid substitutions of HA protein from influenza B clinical isolates detected in Mongolia during 2013–2016.

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Table 2.

Antigenic relationship between B/Victoria isolates and B/Brisbane/60/2008 and amino acid substitutions on HA1 gene, refer to B/Brisbane/60/2008 strain.

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Table 3.

Antigenic relationships between B/Yamagata isolates and B/Wisconsin/01/2010, B/Massachusetts/02/2012 and B/Phuket/3073/2013 and amino acid substitutions on HA1 gene, refer to B/Wisconsin/01/2010 strain.

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Table 4.

Result of fluorescence-based NA inhibition assay.

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Fig 5.

The compared result of drug resistant strains, NA protein sequences with clinical specimens and strain B/Kochi/61/2011.

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