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Fig 1.

The thrombomodulin−protein C receptor (TM-EPCR) system located on the endothelial surface.

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Table 1.

Characteristics of participating studies.

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Table 1 Expand

Table 2.

PROCR association results of lead LD SNPs in Discovery GEOS European-Americans for all-stroke detailing allelic variants, effect allele frequencies (EAF) and as stratified by the absence or presence of vascular risk factors, and lead LD SNP young-onset replication results.

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Table 2 Expand