Fig 1.
Tau and NF-L concentrations do not change following uncomplicated SRC.
(A) Tau concentrations at baseline, and at 6- and 14-days following uncomplicated SRC. (B) NF-L concentrations at baseline, and at 6- and 14-days following uncomplicated SRC.
Fig 2.
Tau and NF-L concentrations at preseason and following uncomplicated SRC (all time points).
(A) Tau concentrations were unchanged in post-concussion samples (all times) compared to preseason samples. (B) There was no difference between preseason and post-concussion (all times) NF-L concentrations.
Table 1.
Biomarker concentrations and SCAT3 metrics before and after sport-related concussion.
Fig 3.
Total number of symptoms and symptom severity scores assessed by SCAT3 at preseason and following uncomplicated SRC.
(A) The total number of symptoms reported on the SCAT3 increased from preseason to 6-days following uncomplicated SRC and returned to baseline at 14-days. Maximum possible number of symptoms is 22. (B) Symptom severity scores increased at 6-days following uncomplicated SRC compared to baseline and returned to baseline at 14-days following injury. Maximum possible symptom severity score is 132.
Fig 4.
Total number of errors on the balance error scoring system (BESS) at preseason, and 6- and 14-days following uncomplicated SRC.
The total number of errors assessed by the BESS was unchanged following uncomplicated SRC compared to preseason values. The BESS is calculated by adding one point per error during 3 separate 20-second tests.
Fig 5.
Total number of correct answers on the standardized assessment of concussion (SAC) at preseason, and 6- and 14-days following uncomplicated SRC.
Total number of correct answers, out of 31, was unchanged following uncomplicated SRC compared to preseason values.