Fig 1.
Most important characteristic landmarks of pulse wave profile with the definitions of parameters derived from the waveform.
Table 1.
Basic characteristics of the studied group of patients with biochemical measurements in blood serum at the end of midweek hemodialysis session.
Fig 2.
Measurement schedule and average peripheral and aortic pulse wave profiles.
(A) Pressure profile was recorded 8 times in each of 35 patients before the start, after the start, before the end and after the end of hemodialysis (HD) performed after 3-day and 2-day interdialytic periods. Presented are (B) average recorded peripheral and (C) reconstructed aortic pulse waves scaled to the one heartbeat with pooled data for hemodialysis performed after 3-day and 2-day interdialytic intervals. Characteristic points of pulse waveform shown in Fig 1 are less noticeable here due to averaging of individual profiles. For the parameter values see S1 Table.
Fig 3.
Statistically significant changes in the aortic pulse wave shape caused by hemodialysis.
Changes of aortic pulse wave when comparing profile before the start and right before the end of hemodialysis session. The time was scaled to one heartbeat and pooled data for hemodialysis performed after 3-day and 2-day interdialytic are presented. For the parameter values see S1 Table.
Fig 4.
Augmentation index and subendocardial viability ratio before, during and after hemodialysis.
(A) Augmentation index and (B) subendocardial viability ratio (SEVR) before the start, after the start, before the end and after the end of hemodialysis session (HD) performed after 3-day and 2-day interdialytic intervals. Statistically significant difference with p-value < 0.001 was marked as ‘***’.
Table 2.
Weight, blood volume and water pools of the body after 3-day and 2-day interdialytic periods.
Fig 5.
Correlation between absolute changes in SEVR and changes of overhydration, reduction of blood volume and ultrafiltration rate.
Correlation between the change in subendocardial viability ratio (SEVR) and the change of overhydration (OH), (A), the percentage change in blood volume (BV), (B), and ultrafiltration rate (C). Shown is also correlation between overhydration (OH) and the percentage change in blood volume (BV) during hemodialysis (HD), (D). Symbols ‘***’, ‘**’, and ‘*’ denote p-value < 0.001, p-value < 0.01, and p-value < 0.05, respectively.
Table 3.
Parameters of aortic pulse wave (mean ± SD) derived before start, after start, before end and after end of hemodialysis (HD) performed after 3-day and 2-day interdialytic intervals, compare Figs 1 and 2.