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Table 1.

Characteristics of study subjects (n = 51).

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Table 2.

Association of investigated brain structure volumes with zBMI.

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Fig 1.

Region of interest voxel-based morphometry analysis of gray matter mass (GMM) in the bilateral mask of amygdala.

Red-yellow shows voxels demonstrating significant inverse association between GMM and BMI z-score at T4 (i.e. at the day of MRI) after controlling for age, sex and intracranial volume. Color bar represents P-values corrected for multiple comparisons using “threshold-free cluster enhancement”. The map of P-values was thresholded using corrected P≤0.05. The background image is the MNI152 standard space T1 template. X-, Y- and Z-values indicate the MNI slice coordinates in millimeter. Images are shown in radiological convention.

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Fig 1 Expand

Fig 2.

Whole-brain voxel-based morphometry analysis of gray matter density (GMD).

Red-yellow shows voxels demonstrating significant inverse association between GMD and BMI z-score at T4 (i.e. at the day of MRI) after controlling for age and sex. Color bar represents P-values corrected for multiple comparisons using “threshold-free cluster enhancement”. The map of P-values was thresholded using corrected P≤0.01. The background image is the MNI152 standard space T1 template. X-, Y- and Z-values indicate the MNI slice coordinates in millimeter. Images are shown in radiological convention.

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Fig 2 Expand