Fig 1.
HTX: heart transplantation, LTX: lung transplantation, ECMO: extracorporeal membrane oxygenation, VAD: ventricular assist device.
Table 1.
Patient demographics and perioperative data.
Fig 2.
Comparison of receiving operating curves (ROC) for prediction ICU-mortality.
Comparison of receiving operating curves (ROC) for prediction of ICU-mortality. Lactate AUROC = 0.79 (95%-CI 0.77–0.82); base excess AUROC = 0.72 (95%-CI 0.69–0.74), p = 0.27.
Table 2.
Univariate and multivariate Cox proportional hazard regression models for patients variables.
Fig 3.
Scatterplot of lactate and base excess levels at admission on ICU after cardiac surgery.
1st group: Lactate ≤3.9mmol/l and BE > -6.7 (n = 887): r = -0.1, p = 0.002, 95%-CI -0.17 to –0.04 2nd group: Lactate ≤3.9mmol/l and BE ≤ -6.7 (n = 28): r = -0.06, p = 0.78, 95%-CI -0.42 to 0.32 3rd group: Lactate >3.9mmol/l and BE > -6.7 (n = 96): r = -0.06, p = 0.58, 95%-CI -0.27 to 0.15. 4th group: Lactate >3.9mmol/l and BE ≤ -6.7 (n = 47): r = -0.36, p = -0.01, 95%-CI -0.59 to -0.08 Overall correlation (n = 1058): r = -0.48, p<0.0001, 95%-CI -0.52 to -0.43.
Table 3.
Hazard ratios with 95% confidence intervals and medians for combinations of lactate and base excess.