Table 1.
Nine potential challenge agents suggested by NIOSH in the draft protocola [11].
Table 2.
Physicochemical data for some commonly used hazardous drugs.
Fig 1.
Calibration plot for 2-phenoxyethanol by automated thermal desorption gas chromatography mass spectrometry.
Fig 2.
Biopharma Stability Testing Laboratory modified National Institute for Occupational Safety and Health test chamber with aluminum extension piece.
Table 3.
CSTD containment performance data using 2.5% v/v 2-phenoxyethanol (2-POE) as challenge agent according to draft NIOSH protocol and defined tasks: task 1 (n = 5) and task 2 (n = 5) performed under IFU conditions.
Fig 3.
Typical gas chromatogram for 2-phenoxyethanol with mass spectrometry (selected M/Z values: 77, 94, and 138) detection.
Fig 4.
Liquid droplets observed on the membrane of ChemoClave CSTD following task 2.