Table 1.
Baseline patient demographic characteristics.
Table 2.
CT-based radiological appearance according to the grading scale of RILI.
Fig 1.
Concordance CT appearance, case 1.
(a) The shadow extends to the right middle and lower lobes beyond the high-dose region; this was diagnosed as diffuse consolidation at 6 months after SBRT. (b) The shadow shows consolidation, volume loss and bronchiectasis; this was diagnosed as the modified conventional pattern at 21 months after SBRT. (c) The shadow remained at 45 months after SBRT.
Fig 2.
Concordance CT appearance, case 2.
(a) Before SBRT, the lung tumor was located in the right upper lobe. (b) The consolidation expands beyond the high-dose region; this shadow was diagnosed as diffuse consolidation at 5 months after SBRT. (c) The shadow shrank, and only a linear opacity remained. This shadow was diagnosed as a scar-like pattern at 20 months after SBRT.
Fig 3.
Concordance CT appearance, case 3.
(a) Before SBRT, the lung tumor was located in the right upper lobe. (b) Patchy areas of hazy and consolidation are seen; this shadow was diagnosed as patchy consolidation and GGO at 5 months after SBRT. (c) The shadow forms a focal consolidation; this was diagnosed as a mass-like pattern at 17 months after SBRT. (d) The shadow shrank, but a mass-like shadow remained at 35 months after SBRT.
Fig 4.
Concordance CT appearance, case 4.
(a) Before SBRT, the lung tumor was located in the left lower lobe. (b) Patchy areas of hazy are seen; this shadow was diagnosed as patchy GGO at 3 months after SBRT.
Table 3.
Early CT appearance pattern as judged by the two observers.
Table 4.
Late CT appearance pattern as judged by the two observers.
Table 5.
CT-based late radiographic grading of RILI as judged by the two observers.
Table 6.
Univariate analyses (Cox regression) for grade 2 or more (the grading was based on the radiographic grading of RILI assessed by observer 1).
Table 7.
Multivariate analyses (Cox regression) for grade 2 or more (the grading was based on the radiographic grading of RILI assessed by observer 1).