Fig 1.
CAV indicates cardiac allograft vasculopathy; FUP, follow-up; QCA, quantitative coronary angiography; ISHLT, International Society of Heart and Lung Transplantation.
Fig 2.
Serial 3-vessel quantitative coronary angiography analysis.
This figure shows the serial quantitative coronary angiography analysis within matched regions of all coronary artery segments at baseline, at 1 year follow-up, and at latest available angiographic follow-up. Coronary artery segments were classified according to the modified AHA/ACC classification. MLD indicates minimal lumen diameter; %DS, percent diameter stenosis.
Table 1.
Baseline clinical characteristics.
Fig 3.
Serial 3-vessel quantitative coronary angiography analysis.
Box-plot representation of minimal lumen diameter and maximal percent diameter stenosis at baseline (median 0.14 years [0.12 to 0.16], at 1 year (median 1.17 years [1.14 to 1.20]) and at long-term angiographic follow-up (median 8.61 years [8.24 to 8.99]) after HTx. Lower and upper box edges are the quartiles and thick line is the median.
Table 2.
QCA analysis of serial angiography at baseline, 1 year and long-term follow-up after heart transplantation.
Fig 4.
Quantitative angiographic analysis.
Box-plot representation of the per-patient mean angiographic change in minimal lumen diameter (minimal lumen diameter 1 year—minimal lumen diameter baseline and minimal lumen diameter latest angiographic follow-up—minimal lumen diameter baseline) from coronary artery segments that were serially assessed and matched. The analysis is stratified according to absence (n = 16) or presence (n = 25) of ISHLT-CAV at 1 year, and at latest angiographic follow-up (median 8.61 years [8.24 to 8.99]). Lower and upper box edges are the quartiles and thick line is the median. A horizontal reference line at change = 0 is drawn.
Table 3.
Baseline clinical characteristics in patients with and without ISHLT-CAV at latest follow-up.