Fig 1.
Schematic illustration showing four different groups of computed tomography (CT)-tumor depth.
(A) Group 1, tumors confined to the stomach wall without extramural tumor infiltration. (B) Group 2, transmural involvement of the tumor with minimal extramural infiltration less than 1 mm. (C) Group 3, transmural involvement of the tumor with 1 mm or more spiculated extramural infiltration. (D) Group 4, transmural involvement of the tumor with nodular extramural infiltration.
Fig 2.
Axial images of contrast enhanced computed tomography (CT) demonstrating four different groups of CT-tumor depth.
Group 1, 2, 3 and 4 in (A), (B), (C), and (D), respectively.
Table 1.
Patient characteristics of included 394 patients.
Table 2.
Incidence of patients with pathologic serosal exposure and advanced nodal status among each subcategory of CT-tumor depth.
Table 3.
Multivariable regression analysis of disease recurrence.
Fig 3.
Prediction tree model for disease recurrence using recursive-partitioning analysis.
Preoperative tumor size and CT-tumor depth were the two major discriminating factors for predicting disease recurrence.
Fig 4.
Kaplan-Meyer curves for disease free survival stratified to variable radiologic parameters.
DFS was significantly worse in patients with CT findings of more advanced CT-tumor depth, CT-LN status, CT-detected EMVI, large size, non-localized longitudinal extent, and Borrmann type 4.
Table 4.
Multivariate cox regression model of disease free survival using clinicoradiologic factors.
Fig 5.
Subgroup analysis among patients with pT4a stage.
As extramural tumor infiltration progressed, recurrence rate significantly increased (A) and the disease free survival became worse (B).