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Fig 1.

Consolidated standards of reporting trials (CONSORT) for cluster and cross sectional cohorts.

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Fig 2.

Cluster design.

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Fig 3.

Intervention components according to the TIDieR guidelines.

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Table 1.

Baseline characteristics of patients in the cluster cohort.

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Table 1 Expand

Table 2.

Baseline measures in cluster cohort.

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Table 3.

Primary outcome measure (intention to treat analysis).

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Table 4.

Secondary outcomes in the cluster cohort (intention to treat analysis).

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Table 4 Expand