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Table 1.

Overview of study design and visits.

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Fig 1.

Study flow chart.

Participants were recruited through posters, newspaper ads and web-based advertisements such as Craigslist and Kijiji. 498 participants were phone screened, 67 were eligible and came in for in person assessment, 28 participants were enrolled, and the results of 27 participants were analyzed.

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Fig 2.

Number of cigarettes/day during quit attempt weeks.

Self-reported number of smoked cigarettes per day for 7 days at baseline (black bars), during the quit attempt week taking gemfibrozil (pattern bars) and during the quit attempt week taking placebo (grey bars). After comparing the effects of both treatments using a linear mixed model, the number of smoked cigarettes/day was significantly higher during baseline compared to both treatments (< 0.001). No significant difference was detected between gemfibrozil and placebo groups.

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Fig 3.

Nicotinized cigarette percent choice: Percent choice of Nicotinized cigarette puffs during the forced choice paradigm showing no significant difference between gemfibrozil (77%) and placebo (79%).

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