Fig 1.
Scatter plot of the 4Kscore by PIRADS and biopsy results among 300 men who had a 4K score and a MRI for evaluation of prostate cancer.
Table 1.
Patient demographics and clinical characteristics among 300 men who underwent an MRI and 4Kscore for evaluation of prostate cancer.
Fig 2.
Probability of Gleason 7 cancer based on the 4Kscore and mpMRI findings among the 149 men who had mpMRI and 4Kscore and underwent biopsy of the prostate.
It appears that the likelihood of Gleason 7 cancer is predicted best by the mpMRI, and the 4Kscore provides a more granular assessment of risk, within each mpMRI category.
Fig 3.
Decision curve analysis comparing clinical utility of 4Kscore, mpMRI and both 4Kscore and mpMRI for detecting clinically relevant cancer.
The curve with the highest net benefit at each threshold probability is the strategy that has the best clinical utility for deciding on the need for a biopsy of the prostate.
Table 2.
The following table reports the impact of the following 5 strategies of using the 4Kscore and/or mpMRI to determine the need for a biopsy of the prostate among 149 men who had a 4Kscore, mpMRI and biopsy of the prostate.