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Table 1.

Patients characteristics.

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Table 2.

Functional and anatomical outcomes.

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Table 2 Expand

Fig 1.

ROC curve for prediction of improvement in visual acuity following PPV with ILM-peeling.

The sensitivity and specificity of timing until surgery and the presence of subretinal fluid in predicting the chance of gaining ≥5 letters BCVA 24 months after surgery. The area under the ROC curve was 0.828.

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Table 3.

Confounders for improvement in BCVA ≥ 5 letters after 12 and 24 months.

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Fig 2.

Biomarkers for visual outcome: OCT scans before and 24 months after PPV with ILM peeling.

2A-B. Patient presenting with biomarkers for good visual outcome, who had early intervention A. SD-OCT showing diffuse DME with subretinal fluid and intact inter-outer segment layer at baseline. B. 24 months after surgery complete resolution of intra- and subretinal fluid. 2C-D. Patient presenting without biomarkers for good visual outcome, who had late intervention. C. SD-OCT showing diffuse DME without subretinal fluid and damaged inter-outer segment layer at baseline. D. Persistent perifoveal intraretinal fluid and damaged inter-outer segment layer 24 months after surgery. Final CST measured <220 μm.

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