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Table 1.

Clinical and demographic characteristics of the 30 included patients with S. aureus orthopaedic device-related infection.

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Table 2.

Virulence factor gene contents of all characterized strains grouped by clonal complex.

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Fig 1.

Comparison of the kinetics of biofilm formation of the main S. aureus clonal complexes (CCs).

(A) Kinetics of early biofilm formation measured using BioFilm Ring Test®: means and corresponding standard errors of three assays of duplicate samples. (B) Amounts of biofilm formed after 24 h measured by crystal violet assays (optical density at 620 nm, OD620): means and corresponding standard errors of three assays of quadruplicate samples.

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Fig 1 Expand

Fig 2.

Comparison of the role of specific components on early biofilm formation for the main S. aureus clonal complexes (CCs).

Results are expressed as relative differences (Eq 1) in the amounts of biofilm (measured using BioFilm Ring Tests®) formed after 6 h incubation in the presence of (A) DNase or (B) proteinase K versus in their absence. The values shown are means and the corresponding standard errors of three assays of duplicate samples.

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Fig 3.

Biofilm minimal inhibitory concentration (bMIC) susceptibility profiles of the main S. aureus clonal complexes to (A) cloxacillin, (B) teicoplanin and (C) vancomycin. The dotted lines shown the mean percentage of susceptible strains to the corresponding antibiotic for all the CCs (n = 30).

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Fig 3 Expand