Fig 1.
CONSORT flow chart.
Table 1.
Postoperative complications.
Table 2.
Patient and surgical characteristics.
Table 3.
Perioperative characteristics.
Fig 2.
Inflammatory cytokine analysis of IL-6, IL-8 and IL-10 pre-operatively (pre-OP), at wound closure (end of surgery) and 24 hours after the end of surgery (24 hours postop).
Red box plots represent the data of the complication group, black box plots represent data of the complication-free group. Data are median and interquartile range. Exact p-values are given.
Fig 3.
Receiver operating characteristic curves for the development of postoperative complications for inflammatory biomarkers.
T1 = at wound closure; T2 = first postoperative day; (A.) area under the curve = 0.65; 95% confidence interval: 0.51–0.78; (B.) area under the curve = 0.68; 95% confidence interval: 0.54–0.82; (C.) area under the curve = 0.64; 95% confidence interval: 0.52–0.76; (D) area under the curve = 0.63; 95% confidence interval: 0.49–0.77.
Table 4.
Multivariate regression analysis for IL-8.
Table 5.
Multivariate regression analysis for patients with IL-8 and IL-6 levels above the 3rd quartile 24 hours after surgery.