Fig 1.
Growth curves of AUC C-peptide versus time since diagnosis in individual patients (coloured lines), with AUC plotted on the (a) original, (b) logarithmic and (c) square root scale. The corresponding mean curves (white) from the fitted SITAR models are shown superimposed.
Fig 2.
Growth curves of AUC C-peptide for the √AUC model shown unadjusted (gray) and SITAR adjusted (colour), with the mean curve (white).
Fig 3.
Histograms of the SITAR random effects (a) mean level and (b) rate of fall, and (c) scatterplot of rate of fall versus mean level.