Table 1.
Patients’ subdivision according to the haemodynamic classification of pulmonary hypertension due to left heart disease.
Table 2.
Patients’ general characteristics.
Table 3.
Patients’ invasive hemodynamic profile.
Fig 1.
Effects of varying the diastolic pressure gradient and pulmonary artery wedge pressure on the compliance-resistance relationship in patients with pulmonary hypertension.
Panel a): pulmonary arterial compliance as a function of pulmonary vascular resistance, both logarithmically transformed. Panel b): resistance-compliance product as a function of pulmonary artery wedge pressure. Ca = pulmonary arterial compliance; DPG = diastolic pressure gradient; PAH = pulmonary arterial hypertension; PH-LHD = pulmonary hypertension due to left heart disease; PVR = pulmonary vascular resistance; RC-time = pulmonary vascular resistance-compliance product.
Table 4.
Right ventricular function in the different haemodynamic subgroups.
Fig 2.
Prevalence of echocardiographic signs of right ventricular dysfunction in the four groups of patients as a function of pulmonary haemodynamics: pulmonary vascular resistance (panel a), diastolic pressure gradient (panel b), and pulmonary arterial compliance (panel c). Ca = pulmonary arterial compliance; CpcPH = combined post- and pre-capillary pulmonary hypertension; DPG = diastolic pressure gradient; Interm = intermediate; IpcPH = isolated post-capillary pulmonary hypertension; PAH = pulmonary arterial hypertension; PVR = pulmonary vascular resistance; RV = right ventricle.
Fig 3.
Kaplan-Meier curves of survival for patients with pulmonary arterial hypertension and patients with pulmonary hypertension due to left heart disease.
In the panel a) patients with pulmonary hypertension due to left heart disease are all pooled together, while in the panel b) they are subdivided in three groups according to the diastolic pressure gradient and pulmonary vascular resistance. CpcPH = combined post- and pre-capillary pulmonary hypertension; Interm = intermediate PH-LHD; IpcPH = isolated post-capillary pulmonary hypertension; PAH = pulmonary arterial hypertension; PH-LHD = pulmonary hypertension due to left heart disease.
Table 5.
Univariate and multivariate predictors of survival in pulmonary hypertension due to left heart disease.