Fig 1.
Inclusion flow diagram of the male CPP cohort.
Table 1.
Baseline characteristics of the cohort.
Table 2.
Underlying etiology of CNS-CPP in 32 boys.
Fig 2.
Baseline LH, FSH, and total testosterone (Testo) levels and testicular volume in CNS-CPP and iCPP cases.
Means and 95CI overlay raw data points. Red dots represent measures from the 3 patients in whom the diagnosis of CPP unmasked a brain neoplasm. Gray lines represent assay lower limits of detection. P-values reflect group comparisons using generalized linear models. To convert to SI units, multiple Testo by 0.0347.
Fig 3.
Number of male patients with CPP, male patients with premature pubarche, and male patients (all diagnoses) seen per annum by BCH Endocrinology.
Note different y-axes scales.