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Fig 1.

Chemical structure of VB3 and VB7.

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Fig 1 Expand

Fig 2.

The synthesis procedure of AEAO.

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Fig 2 Expand

Fig 3.

The extraction process of tea samples.

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Fig 3 Expand

Table 1.

Box-Behnken design and observed response.

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Table 1 Expand

Fig 4.

Scheme of derivation reaction of AEAO with VitaminB7.

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Fig 4 Expand

Table 2.

Estimated regression coefficients for the quadratic polynomial model and ANOVA for the experimental results in the optimization of flavonoids extractions.

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Table 2 Expand

Fig 5.

The 3D response surface of peak area affected by varying derivatization temperature and time(a), varying derivatization temperature and EDC dosage (b), derivatization time and EDC dosage (c).

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Fig 5 Expand

Fig 6.

The representative chromatograms for blank (a) spiked blank with standard VB3(b),VB7(c), VB3 and VB7(d), and tea samples (e).

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Fig 6 Expand

Table 3.

Linear range, correlation coefficient, precision, accuracy, quantitative limits, detection limits and repeatability.

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Table 3 Expand

Table 4.

Main content of VB3 and VB7 in the tea.

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Table 4 Expand

Table 5.

Comparisons of the proposed method with previously reported methods.

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Table 5 Expand