Fig 1.
Representative images of RSI scoring for CXR and CT images.
RSI scores are labelled within each panel. Panels (A)-(C) show CXR images from an individual patient in order of increasing severity. Panels (D)-(F) show CT images from a different individual patient in order of increasing severity.
Table 1.
Scoring algorithm for the Radiologic Severity Index.
Fig 2.
Enrollment flow chart for patients with parainfluenza virus (PIV)-associated lower respiratory tract infection (LRI) included in this study for analysis. BAL = bronchoalveolar lavage.
Table 2.
Baseline characteristics by 30-day survival status.
Table 3.
Characteristics of patients with hematopoietic stem cell transplants.
Fig 3.
Trends in mean Radiologic Severity Index (RSI) scores over time in non-survivors (A) and survivors (B).
(A) Trends in mean RSI scores are shown for patients who died within 14 days (solid circles, n = 4), patients who died between days 15 and 28 (solid squares, n = 5), and patients who died after day 28 (solid triangles, n = 2). (B) Trends in mean RSI scores are shown for survivors.
Table 4.
Univariate and multivariate cox regression models for the prediction of 30-day mortality.
Table 5.
Univariate logistic regression models for the prediction of 30-day mortality with baseline RSI, peak RSI and delta-RSI with RSI-CXR scores.
Table 6.
Univariate logistic regression models for the prediction of 30-day mortality with baseline RSI, peak RSI and delta-RSI with any RSI score.
Fig 4.
Bland-Altman plots for agreement between expert radiologists.
Bland-Altman plots for agreement between expert radiologists in (A) RSI, (B) RSI scores restricted to computed tomography (CT) only (RSI-CT), and (C) RSI scores restricted to chest x-ray (CXR) measurements only (RSI-CXR). Upper and lower gray bars show 95% confidence intervals for upper and lower limits of agreement. Center gray bar shows 95% confidence intervals for bias. Solid line represents the slope of the bias (p = NS).
Table 7.
Distribution of radiologic patterns in chest X-rays and chest computed tomography scans.
Table 8.
Agreement between readers for RSI scores.
Fig 5.
Bland-Altman plots for agreement between RSI-CXR and RSI-CT.
Upper and lower gray bars show 95% confidence intervals for upper and lower limits of agreement. Center gray bar shows 95% confidence intervals for bias. Solid line represents the slope of the bias (slope = 0.38; p = 0.0008). RSI-CXR systematically underestimates RSI-CT at low RSI scores and overestimates RSI-CT at high RSI scores.
Table 9.
Agreement between RSI-CXR and RSI-CT.