Fig 1.
Study flow.
Table 1.
Demographics of enrolled subjects (full analysis set).
Fig 2.
FEV1 improvement after 12 weeks in FAS (A) and PPS analysis (B).
The t-test or Wilcoxon’s signed rank test were used to analyze improvement within groups, and ANCOVA was used for comparisons of improvement between the two groups. The data are presented as the mean (dot) and standard error of the mean (bar). FEV1, forced expiratory volume in the 1st second; FAS, full analysis set; PPS, per-protocol set.
Fig 3.
FEV1 improvement in the FAS (A) and PPS (B), ACT improvement in the FAS (C) and PPS (D), and inhaler technique score improvement in the FAS (E) and PPS (F).
The t-test or Wilcoxon’s signed rank test were used to analyze improvement within groups, and ANCOVA was used for comparisons of improvement between the two groups. The data are presented as the mean (dot) and standard error of the mean (bar). FEV1, forced expiratory volume in the 1st second; ACT, asthma control test; FAS, full analysis set; PPS, per-protocol set.
Table 2.
Other secondary outcomes at 4 weeks and 12 weeks according to the group.
Table 3.
Subgroup analysis for primary outcome (FEV1, %) according to age and baseline ACT score.