Fig 1.
Non-invasive and invasive preimplantation genetic testing workflow.
Fig 2.
Three examples comparing TE biopsy, NIPGS and WB from the same vitrified-thawed embryo.
Fig 2A, 2B and 2C show consistent results between TE biopsy, NIPGS and WB samples. Size of segmental loss detected in 2C was smaller in the WB sample compared with the TE and NIPGS samples (37.15 Mb vs. 53.69 Mb).
Table 1.
Summary of NGS results from NIPGS, TE and WB samples obtained from the same blastocyst.
Table 2.
Concordance of blastocyst ploidy and karyotype per sample and per chromosome assessed by NIPGS vs TE vs WB.
Fig 3.
One example comparing TE biopsy and NIPGS from the same freshly cultured embryo.
Fig 3A and 3B show consistent results between TE biopsy and NIPGS samples for this embryo.
Table 3.
Summary of NGS results from NIPGS and TE samples obtained from the same blastocyst in fresh cases.
Table 4.
Concordance of blastocyst ploidy and chromosomal aberrations per sample and per chromosome assessed by NIPGS vs. TE biopsy.