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Table 1.

Composition of basal diet fed to rats, %.

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Table 2.

Experimental schemaa (provided copper dosage was calculated taking into account CuCO3 in MX or copper from Cu nanoparticles preparation).

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Table 2 Expand

Table 3.

Composition of mineral mixtures (MX) used in experimental diets, g/kg.

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Table 3 Expand

Table 4.

Copper excretion patterns in the digestibility and utilisation test as well as Cu concentration in liver and brain tissues.

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Table 4 Expand

Table 5.

Dietary intake, final body weight (BW), proportion of body fat and lean mass, and relative weights of selected internal organ of rats.

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Table 5 Expand

Table 6.

Activity of microbial enzymes in caecal digesta of rats (μmol/h/g fresh caecal digesta).

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Table 7.

Activity of microbial enzymes in caecal digesta of rats (μmol/h/g fresh caecal digesta).

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Table 7 Expand

Table 8.

Activity of selected enzymes in plasma of rats fed experimental diets (U/l).

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Table 9.

The relative weight of small intestine with contents, measurements of jejunal villi and crypts in experimental rats as well as basic caecal indices.

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Table 9 Expand

Fig 1.

Morphological effects of different Cu sources on rat intestine—(A) CuD group; (B) CuS-H, CuS-L i CuNP-L groups; (C) CuNP-H group (magnification 10×).

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Fig 1 Expand

Table 10.

Short-chain fatty acid (SCFA) concentration and profile in the caecal digesta of rats.

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Table 10 Expand

Fig 2.

Morphological effects of different Cu sources on rat liver.

(A-B) CuD group showing low-grade hydropic degeneration (A, magnification10×; B, magnification 10×); (C-D) CuS-H, CuS-L i CuNP-L groups showing medium-grade hydropic degeneration (C, magnification 20×; D, magnification 4×); (E-F) CuNP-H group showing high-grade hydropic degeneration and necrotic lesions (E, magnification; 20×; F, magnification 4×). Experimental groups: see Table 2.

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