Table 1.
Baseline characteristics of the study population (N = 556).
Table 2.
Associations between urinary free light chain/creatinine ratios and albumin/creatinine ratio with other baseline variables.
Fig 1.
Scatter plots of urinary kappa/creatinine ratio (a) and lambda/creatinine ratio (b) by estimated glomerular filtration rate.
Scales are logarithmic. Abbreviations: GFR = glomerular filtration rate.
Fig 2.
Scatter plots of urinary kappa/creatinine ratio (a) and lambda/creatinine ratio (b) by urinary albumin/creatinine ratio.
Scales are logarithmic.
Fig 3.
Scatter plots of urinary kappa/creatinine ratio by serum kappa (a) and urinary lambda/creatinine ratio by serum lambda (b).
Scales are logarithmic.
Fig 4.
Restricted cubic splines of the subhazard ratio (solid line, with 95% confidence intervals shown as interrupted lines) of end stage renal disease by urinary kappa/creatinine ratio (a) and urinary lambda/creatinine ratio (b), adjusted for the competing risk of death.
Percentiles are shown as vertical dotted lines. Abbreviations: P = percentile.
Fig 5.
Cumulative incidence of end stage renal disease by quartiles of urinary kappa/creatinine ratio (a) and lambda/creatinine ratio (b).
Abbreviations: ESRD = end stage renal disease; KCR = kappa/creatinine ratio; LCR = lambda/creatinine ratio; Q = quartile.
Table 3.
Subhazard ratios with 95% confidence intervals in univariable competing-risk models for risk of end stage renal disease accounting for the competing risk of death.
Table 4.
Subhazard ratios with 95% confidence intervals for urinary free light chain/creatinine ratios as continuous and categorical (above 75th centile) predictors in multivariable competing risk models for end-stage renal disease, adjusted for the competing risk of death.
Table 5.
Logistic regression models for the prediction of end stage renal disease at two years, with measures of model performance and the incremental value of adding kappa/creatinine ratio (KCR) or lambda/creatinine ratio (LCR) to a baseline model containing the kidney failure risk equation (KFRE).