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Table 1.

SNOT-16 questionnaire[17,28].

Rate how much you have been bothered, in terms of severity and frequency, by the following symptoms.

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Fig 1.

CONSORT flowchart of study participants.

Reasons for exclusion before randomization were mostly inferred from chart review. We had 30 dropouts during the course of the study. Reason for dropping out included failure to improve or worsening illness (12), adverse reaction (10), allergic reaction (2), fear of side effects (2), misplaced medication bottle (1), switched to different antibiotic for another infection (1), tablet size too large (1), self-discontinuation because of marked symptom improvement (1), and unknown (1). Some participants had multiple reasons for exclusion or for dropping out.

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Table 2.

Baseline characteristics of participants as a whole by dose.

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Table 3.

Baseline characteristics by Time Period and Dose.

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Table 4.

Efficacy by Time Period and Dose.

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Table 5.

Adverse effects by Time Period and Dose.

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Table 6.

Reasons for not taking antibiotic again*.

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Table 7.

Bacterial colonization*.

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