Table 1.
Criteria for categorization of patients into various categories of the composite reference standard.
Fig 1.
Flow-chart showing the study design and patient flow in the study.
NOTE. EPTB, extrapulmonary tuberculosis; TB, tuberculosis; CT, computed tomography; FNAC, fine-needle aspiration cytology. a Not included in the composite reference standard.
Table 2.
Demographic and baseline characteristics of the 126 categorized study participants, n(%).
Fig 2.
Patterns of immunostaining with anti-MPT64 antibody in various specimens.
The signals are seen as granular, reddish staining. A, fine-needle aspirates from lymph nodes, signals were extracellular probably due to cell lysis (A1), mostly intracytoplasmic (A2-A3), and in necrotic areas (A4); B, pleural effusion, intracytoplasmic staining; C1-C2, pus/abscess, intracytoplasmic staining; C3-C4, pericardial effusion, intracytoplasmic staining, and non-specific staining mainly of red blood cells; D1-D2, ascites, intracytoplasmic staining (D1), extracellular probably due to cell lysis (D2); D3-D4, cerebrospinal fluid, extracellular probably due to cell lysis.
Table 3.
Results of diagnostic procedures in effusions, CSF, aspirates and biopsies.
Table 4.
Diagnostic validation of various procedures among lymphadenitis, pleuritis and children using the CRS as reference standard.
Table 5.
Relationship between various cytomorphological features in fine-needle aspirates from lymph nodes and results of diagnostic procedures.